Lifespan

11 articles

The frontier of longevity science: cellular reprogramming, senolytics, epigenetic clocks, and clinical research extending human lifespan.

Two men in white Longevity Minds T-shirts stand in front of Tokyo Tower

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Longevity Minds Launches a Tokyo Community Built Around Aging

Shuzo Yamamoto and Satotaka Omori are building a Tokyo community of scientists and builders around aging, in a country where nearly 30 percent of people are already over 65.

Editorial Team · Sep 25, 2026 · 4 min read

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Avaí Bio and Austrianova Present an Encapsulated-Cell Approach to α-Klotho

At the Second Annual Klotho Conference, the companies described implanted cells, protected inside Austrianova’s Cell-in-a-Box capsules, that are meant to secrete α-Klotho over a long period.

Anton Dalsätt · Sep 24, 2026 · 3 min read

The Buck Institute for Research on Aging in Novato, California, seen from the courtyard

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Buck Institute Will Use Oracle Health Data to Build an Intrinsic Capacity Score

The Novato institute is applying more than 122 million de-identified longitudinal records to an ARPA-H effort to measure vitality and spot age-related decline earlier.

William Ferreira Andrén · Sep 23, 2026 · 3 min read

Insilico Medicine graphic for the Longevity Vaccines research program

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Insilico Launches Longevity Vaccines Research to Clear Early Drivers of Aging

The program uses generative AI and circular mRNA to design single-dose, self-limiting therapies that direct a patient’s own T cells against the cells that start age-related disease, beginning with the immune system.

Anton Dalsätt · Sep 15, 2026 · 4 min read

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BioViva Secures a U.S. Patent for an hTERT and Follistatin Gene-Therapy Approach

U.S. Patent No. 12,653,907 covers methods that combine hTERT and Follistatin-344 for age-related disorders, including approaches tied to telomere length, muscle mass, and blood glucose.

Anton Dalsätt · Sep 10, 2026 · 3 min read

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Calorie Restriction Reduced DNA Mutations Across the Mouse Genome

Mice fed 30% fewer calories carried fewer DNA mutations in several tissues, with the largest drop in the liver and in the quietest parts of the genome, a Cell study from NYU Langone reports.

William Ferreira Andrén · Sep 9, 2026 · 3 min read

Insilico Medicine graphic for the Nature Biotechnology paper on rentosertib and proteomic aging clocks

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Rentosertib Linked to a Younger Proteomic Age in an IPF Trial

Six proteomic aging clocks, applied to blood samples from a Phase IIa study of Insilico’s AI-designed lung-fibrosis drug, each pointed toward a lower predicted biological age in treated patients.

William Ferreira Andrén · Sep 7, 2026 · 5 min read

White laboratory mice held over a lab bench

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Late-Life Semaglutide Extended Lifespan in Older Female Mice

An NIH-funded study at UC Berkeley found that older female mice given the GLP-1 drug lived a median of nearly 100 days longer than untreated mice, and outperformed a matched calorie-restricted group on memory and blood sugar.

William Ferreira Andrén · Sep 2, 2026 · 3 min read

Claude Science interface showing a biological data visualization beside analysis code

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Anthropic Launches "Claude Science," an AI Workbench Aimed at Biology and Drug Discovery

The company behind Claude has released a research environment that pulls genomics, proteomics, and cheminformatics tools into one place — and is offering academic labs up to $30,000 in credits to try it.

Editorial Team · Jul 1, 2026 · 4 min read

Black-and-white close-up of a human eye and iris

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Life Biosciences Doses First Patient in Landmark Trial of Cellular-Reprogramming Therapy for Vision Loss

ER-100 is one of the first attempts to take partial epigenetic reprogramming — resetting cells to a "younger" state — from the lab into a human trial. The first patient has now been dosed.

Editorial Team · Jun 10, 2026 · 4 min read

Two Fund Longevity demonstrators holding signs calling for aging research funding

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Longevity advocates to rally in 15 cities, demanding governments treat aging as a medical emergency

The April 8 coordinated action calls for dedicated public funding and a regulatory pathway for anti-aging therapies, two things that currently do not exist anywhere in the world.

Editorial Team · Apr 6, 2026 · 4 min read