Longevity Minds Launches a Tokyo Community Built Around Aging
Shuzo Yamamoto and Satotaka Omori are building a Tokyo community of scientists and builders around aging, in a country where nearly 30 percent of people are already over 65.
Editorial Team · 4 min read
Avaí Bio and Austrianova Present an Encapsulated-Cell Approach to α-Klotho
At the Second Annual Klotho Conference, the companies described implanted cells, protected inside Austrianova’s Cell-in-a-Box capsules, that are meant to secrete α-Klotho over a long period.
Anton Dalsätt · 3 min read
Buck Institute Will Use Oracle Health Data to Build an Intrinsic Capacity Score
The Novato institute is applying more than 122 million de-identified longitudinal records to an ARPA-H effort to measure vitality and spot age-related decline earlier.
William Ferreira Andrén · 3 min read
Insilico Launches Longevity Vaccines Research to Clear Early Drivers of Aging
The program uses generative AI and circular mRNA to design single-dose, self-limiting therapies that direct a patient’s own T cells against the cells that start age-related disease, beginning with the immune system.
Anton Dalsätt · 4 min read
BioViva Secures a U.S. Patent for an hTERT and Follistatin Gene-Therapy Approach
U.S. Patent No. 12,653,907 covers methods that combine hTERT and Follistatin-344 for age-related disorders, including approaches tied to telomere length, muscle mass, and blood glucose.
Anton Dalsätt · 3 min read
Calorie Restriction Reduced DNA Mutations Across the Mouse Genome
Mice fed 30% fewer calories carried fewer DNA mutations in several tissues, with the largest drop in the liver and in the quietest parts of the genome, a Cell study from NYU Langone reports.
William Ferreira Andrén · 3 min read
Rentosertib Linked to a Younger Proteomic Age in an IPF Trial
Six proteomic aging clocks, applied to blood samples from a Phase IIa study of Insilico’s AI-designed lung-fibrosis drug, each pointed toward a lower predicted biological age in treated patients.
William Ferreira Andrén · 5 min read
Late-Life Semaglutide Extended Lifespan in Older Female Mice
An NIH-funded study at UC Berkeley found that older female mice given the GLP-1 drug lived a median of nearly 100 days longer than untreated mice, and outperformed a matched calorie-restricted group on memory and blood sugar.
William Ferreira Andrén · 3 min read
Life Biosciences Doses First Patient in Landmark Trial of Cellular-Reprogramming Therapy for Vision Loss
ER-100 is one of the first attempts to take partial epigenetic reprogramming — resetting cells to a "younger" state — from the lab into a human trial. The first patient has now been dosed.
Editorial Team · 4 min read
Longevity advocates to rally in 15 cities, demanding governments treat aging as a medical emergency
The April 8 coordinated action calls for dedicated public funding and a regulatory pathway for anti-aging therapies, two things that currently do not exist anywhere in the world.
Editorial Team · 4 min read
What Longevity Actually Means
Two Goals, One Word, What Does Longevity Mean?
William Ferreira Andrén · 4 min read